THE ROLE OF RECEPTORS TO ESTROGEN AND PROGESTERONE IN PRESCRIPTION OF HORMONAL THERAPY TO PATIENTS WITH BREAST CANCER IN DIFFERENT AGE GROUPS
Abstract
The role of receptors to estrogen and progesterone in prescription of hormonal therapy to patients with breast cancer in different age groups is investigated on materials of Institute of medical radiology by named by S. P. Grigoriev AMSU. It is established, that presence of receptors to an estrogen and progesterone differs depending on age of patients. In premenopausal age estrogenic receptors with weak positive reaction prevail, in postmenopausal age quantity of progesterone receptors increases, whereas at senile age in 80 % of cases receptors are absent. Received data is necessary for taking into account in prescription of hormonal therapy to patients with breast cancer.
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2. Божок А.С., Семиглазов В.Ф., Семиглазов В.В., и др. // Соврем. онкол.- 2005. - T.7.- № 1.- С. 58-63.
3. Вышинская Г.В., Михина З.П., Данилова В.С. // Соврем. онкол. – 2004. - № 6(4). - С. 158-62.
4. Дильман В.М. Эндокринологическая онкология. Рук. для врачей. Изд.2, перераб. и доп. -М.:Мед-книга. - 1983. - 408 с.
5. Заридзе Д.Г. // Вопросы онкологии. - 2002. - Том 48. - № 4-5. - С. 489-495.
6. Онкогинекология /Под ред. З.Ш. Гилязутдиновой, М.К.Михайлова. -М.:МЕДпресс. - 2000. - 383 с.
7. Семиглазов В.Ф. // Практическая онкология. - 2000. - №2 (июнь). - С. 26-30.
8. Сергиенко В.И., Бондарева И.Б. Математическая статистика в клинических исследованиях. -М.: ГЭОТАР. - 2000. - 256 с.
9. Трапезников Н.Н., Аксель. Е. М. Статистика злокачественных заболеваний в России и странах СНГ (состояние онкологической помощи, заболеваемость, смертность). -М. - 2001. - С. 71-76.
10. Beck J.I., Boothroyd C., Proctor M., et al // Cochrane Database of Systematic Reviews - 2005. - Vol. 71. - № 4. - Р. 71-76.
11. Cuzick J, Ambroisine L, Davidson N, et al // Lancet - 2007. - Vol. 369. - Р. 1711-23.
12. Howell A., Cuzick J., Baum M. et al. // Lancet. - 2005. - Vol. 365. - P. 60-62.
13. Wilcken N., Hornbuckle J., Ghersi D. // Cochrane Database of Systematic Reviews. - 2003. - Vol. 83. - № 8. - Р. 411-417.
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