STRUCTURAL CHANGES OF MYOCARDIUM OF LEFT VENTRICLE AND PULSE BLOOD PRESSURE (ACCORDING TO 24-HOUR MONITORING) IN PATIENTS WITH HYPERTENSIVE DISEASE
Abstract
66 male patients (mean age 49,6±3,7 years) with hypertensive disease stages II, 2th and 3th degrees of arterial hypertension were inspected. 24-hour monitoring of blood pressure (BP) and ultrasonic research of heart for the exposure of criteria of hypertrophy was studied. According to the 24-hour monitoring, the of hypertrophy of left ventricle (LVH) and a complex of changes patients were divided into 2 groups: 1) those (n=18) having pulse blood pressure (PBP24)>53 mm Hg and 2) those (n=48) having PBP24<53 mm Hg. Group 1 patients were found to have significantly higher index of mass of left ventricle, LV WRTI, and incidence of LVH and a complex of changes in the BP profile as higher values of 24-hour systolic, diastolic and mean BP, PBP. The correlation analysis revealed a highly significant contribution of PBP24 to the development of LVH.
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2. Лопач С.Н., Чубенко А.В., Бабич П.И. Статистические методы в медико-биологических исследо-ваниях с использованием Exel. -К.:Морион, 2000. - 320 с.
3. Ощепкова Е.В., Зелвеян П.А., Буниатян М..С., др. // Тер. архив. - 2002. - № 12. - С.21-24.
4. Хомазюк И.Н., Златогорская Ж.М., Хомазюк В.А. // Укр. кардиол. журн. - 2003. - № 4. - С.56-61.
5. Asmar R., Ruduichi A., Blacher J. et al. // Am. J. Hypertens. - 2001. - Vol. 14. - P.91-97.
6. Benetos A. // J.Hypertens. - 1999. - Vol.17 (suppl.5). - P.21-24.
7. Boutouyrie P., Bussy C., Lacolley P. et al. //Circulation. - 1999. - Vol.100. - P.1387-1393.
8. Clement D.L. Prognostic value of ambulatory female hypertenives blood pressure: the OVA-study. ESC Congress 2002 in Berlin – Germany, 31 August 4, September 2002.
9. Dart A.M., Gatzka C.D., Kingwell B.A. et al. // Hypertension. - 2006. - Vol.47. - P.785-790.
10. Den Hond E, Staessen J.A. Relation between left ventricular mass and systolic blood pressure at baseline in the APTH and THOP trials. Blood Press Monit. 2003 Aug; 8(4). - Р. 173-175.
11. Franklin S., Khan S., Wong N. et al. //Circulation. - 1999. - Vol.100. - P.354-360.
12. Mancia G., Parati G. // Blood pressure, Suppl. - 2000. - Vol.2. - P. 12-16.
13. Roman M.J., Kitzer J.R., Ali T et al. // Circulation. - 2005. - Vol.112 (suppl II). - P. II 778.
14. Verdecchia P., Schillaci G., Borgioni C. et al. // Hypertension. - 1998. - Vol.32. - P. 983-988.
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