Mass spectrometric study of lactose and n-acetilneuraminic acid adsorbed on the ultrafine silica surface
Keywords:
silica, lactose, N-acetylneuraminic acid, adsorption, temperature programmed desorption mass spectrometry, thermolysis, nanomaterialsAbstract
The aim of the study was investigation of nanomaterials based on N-acetylneuraminic acid (NANA)
adsorbed on ultrafine silica surface modified by lactose and also of components of synthesized
nanomaterial by means of temperature programmed desorption mass spectrometrty. The isotherm of
adsorption of NANA on silica surface modified by lactose was obtained (Аmax~0.6·10- 4 mole/g). It was
shown by TPD MS method that thermal decomposition of NANA occured in three stages. The first one
starts with rupture of NC bond, resulting in formation of HNCH3CO– fragment, with consequent
fragmentation in the ionization chamber of mass spectrometer. As for second and third stages, the
assumption is proposed that thermolysis occurs through rearrangement of six-link cycle into five-link
one. Thermal decomposition of synthesized nanomaterial results in appearance the same components of
mass spectra which are characteristic for lactose, but with different temperature dependencies.
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