The mathematical model of DNA interaction with actinocin antibiotic

Authors

  • N.I.Danylchenko V.N. Karazin Kharkov National University Author
  • S.V.Gatash V.N. Karazin Kharkov National University Author

Keywords:

DNA, derivatives of actinocin, mathematical model, binding constants, method of computational modeling

Abstract

The mathematical model describing the dynamics of DNA interaction with derivatives of actinocin is supposed based on the experimental results collected from investigations of DNA binding with derivatives of actinocin. The influence of hydration on interaction of dye with DNA is determined. It is shown that the received theoretical data is in agreement with experimental results obtained for the humid samples of thymus DNA.

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Author Biographies

  • N.I.Danylchenko, V.N. Karazin Kharkov National University

    4 Svobody Sq., 61077 Kharkov, Ukraine

  • S.V.Gatash, V.N. Karazin Kharkov National University

    4 Svobody Sq., 61077 Kharkov, Ukraine

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Published

2002-06-05

Issue

Vol. 2 No. 11 (2002): Біофізичний вісник

Section

Molecular biophysics

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How to Cite

The mathematical model of DNA interaction with actinocin antibiotic. (2002). Biophysical Bulletin, 2(11), 36-38. https://periodicals.karazin.ua/biophysvisnyk/article/view/18509