Absorption and fluorescent properties of potential fluorescent probes of nucleic acids molecular hybridisation, based on phenazine derivatives
Keywords:
phenazines, spectroscopy, polarized fluorescence, fluorescent probeAbstract
Absorption and fluorescent spectra of imidazo-[4,5-d]-phenazine and its three novel derivatives were studied in ethylacetate and glycerole. Absorption spectra of these derivatives in visible region consist of two bands attributed to different ππ* electronic transitions. Energy values of S1<—S0 electronic transition are calculated for all derivatives. Fluorescence polarization degrees of 2-trifluoridemethylimidazo-[4,5-d]-phenazine and 1,2,3-triazole-[4,5-d]-phenazine are several times higher of that for unsubstituted imidazophenazine, that makes perspective their using as fluorescent probes upon studies of nucleic acid molecular hybridization.
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Published
2018-06-25
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Section
Molecular biophysics
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How to Cite
Absorption and fluorescent properties of potential fluorescent probes of nucleic acids molecular hybridisation, based on phenazine derivatives. (2018). Biophysical Bulletin, 1(12), 49-52. https://periodicals.karazin.ua/biophysvisnyk/article/view/12308
