Ip-spectroscopic study on DNA interaction with Cd2+ ions
Keywords:
DNA, Cd2 ions, IR-spectroscopyAbstract
The IR-spectroscopy method was used to study a DNA interaction with Cd2+ ions in aqueous solution. While interacting with metal ions, DNA with the high concentration transits into the compact structure. Association constants are determined, cooperativity of the Cd2+ ion binding is demonstrated, and nonmonotonous dependence of the binding degree (r) on the concentration of free metal ions (Cf) is ascertained. Binding isotherms are of the S-like binding to DNA molecules is highly cooperative.
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Published
2018-06-25
Issue
Section
Molecular biophysics
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How to Cite
Ip-spectroscopic study on DNA interaction with Cd2+ ions. (2018). Biophysical Bulletin, 1(12), 44-48. https://periodicals.karazin.ua/biophysvisnyk/article/view/12058
