INFLUENCE OF SUBTOXIC DOSES OF COMPLEX ORGANIC MIXTURES, BASED ON GLYCOLS, ON OKSIDATION AND ANTIOKSIDATION SYSTEMS OF WHITE RATS ORGANISM

Автор(и)

  • E. V. Sirenko
  • V. I. Zykov
  • E. A. Kycherenko

Ключові слова:

glycols, oxydation, antioxydation system, adaptation

Анотація

The state of the oxygenation and antioxygenation systems of white rats organism, which got the subtoxic doses of complex organic mixtures, based on the glycols, were investigated in subacute experiment. It was demonstrated, that the action of the organic substances causes the accumulation the diene conjugates (DC), malondialdegyde (МDА) in the blood serum, decreases the activity of the membrainspecific lipid enzymes, glucose-6-phosphatedtgydrogenes, glutationperoxyde, SH-groups of the blood, increases the vitamine C con­tents in the adrenal glands and the glutation in the blood of rats. It was shown the ability of the investigated substances to stimulate the oksidationsystem, that can cause to the exhaustion of antioxydation system and damage the cellular membrane by the active forms of the oxygen. 

Завантаження

Номер

Розділ

Fundamental Research

Як цитувати

INFLUENCE OF SUBTOXIC DOSES OF COMPLEX ORGANIC MIXTURES, BASED ON GLYCOLS, ON OKSIDATION AND ANTIOKSIDATION SYSTEMS OF WHITE RATS ORGANISM. (2016). Вісник Харківського національного університету імені В. Н. Каразіна. Серія «Медицина», 24, 7-12. https://periodicals.karazin.ua/medicine/article/view/6701