CHANGING OF THE DOSE COEFFICIENT OF THE MAJOR GROUPS OF DRUGS FOR PATIENTS WITH IMPLANTED PACEMAKERS, DEPENDING ON THE STAGE OF HYPERTENSION

  • T. A. Derienko V.N. Karazin Kharkiv National University, Kharkiv, Ukraine https://orcid.org/0000-0002-2479-2896
  • D. E. Volkov SI «Zaycev V. T. Institute of General and Urgent Surgery NAMS of Ukraine», Kharkiv, Ukraine
  • D. A. Lopin SI «Zaycev V. T. Institute of General and Urgent Surgery NAMS of Ukraine», Kharkiv, Ukraine
  • M. I. Yabluchansky V.N. Karazin Kharkiv National University, Kharkiv, Ukraine https://orcid.org/0000-0002-4512-6729
Keywords: pacing, the stage of hypertension, the dose rate

Abstract

We observed 131 patients (70 men and 61 women) aged 69,5 ± 11,6 at the annual stage of drug therapy after implantation of pacemakers in the DDD / DDDR modes, VVI / VVIR and CRT-P / CRT-D. Patients were divided into 2 groups – I and II stage of AH. . In each group, the dose rate was defined in major groups of cardiac drugs at every stage of research. The results showed that the dose coefficient of the major groups of cardiac drugs in patients with pacemaker and AH was determined by the stage of AH, what is more AH stage III required higher doses of diuretics and anti-arrhythmic drugs than AH stage II during the hole period of observation. Patients with implanted pacemaker and AH require more careful titration of the major groups of cardiac drugs, taking into account the stage of AH.

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Author Biographies

T. A. Derienko, V.N. Karazin Kharkiv National University, Kharkiv, Ukraine

Svobody sq., 6, Kharkiv, 61022, Ukraine

 
D. E. Volkov, SI «Zaycev V. T. Institute of General and Urgent Surgery NAMS of Ukraine», Kharkiv, Ukraine

Entrance of Balakirev, 1, Kharkiv, Kharkiv region, 61000

D. A. Lopin, SI «Zaycev V. T. Institute of General and Urgent Surgery NAMS of Ukraine», Kharkiv, Ukraine

Entrance of Balakirev, 1, Kharkiv, Kharkiv region, 61000

M. I. Yabluchansky, V.N. Karazin Kharkiv National University, Kharkiv, Ukraine

Svobody sq., 6, Kharkiv, 61022, Ukraine

 

References

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Published
2017-09-11
How to Cite
Derienko, T. A., Volkov, D. E., Lopin, D. A., & Yabluchansky, M. I. (2017). CHANGING OF THE DOSE COEFFICIENT OF THE MAJOR GROUPS OF DRUGS FOR PATIENTS WITH IMPLANTED PACEMAKERS, DEPENDING ON THE STAGE OF HYPERTENSION. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (33), 11-15. Retrieved from https://periodicals.karazin.ua/medicine/article/view/9043
Section
Clinical research

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