INTRAVENOUS INJECTION OF CELLS OF EMBRYONIC LIVER TO RATS WITH ALCOHOL INDUCED HEPATIC INJURY
Abstract
The action of cryopreserved cells of embryonic liver (CEL) on the model of alcohol induced hepatic injury at rats was explored. It is shown that intravenous injection of CEL improves the organism’s general state (enlarges the increase of body weight, improves the hair state) and restores the functional state of liver (normalizes duration of hexenal sleep and prothrombin time, increases albumin content in blood plasm). Indicated results, got on a background of continued alcohol intake.
Downloads
References
2. Ковалёв Г. А., Петренко А.Ю. // Вісник Харківського національного університету ім. В. Н. Каразі-на. Серія Медицина. - 2004. - № 617. - Вип. 8. - С.14-18.
3. Кухарчук А.Л., Радченко В.В., Сирман В.М. Стволовые клетки: эксперимент, теория, клиника. Эмбриональные, мезенхимальные, нейральные и гемопоэтические стволовые клетки. -Черновцы: Золоті литаври. - 2004. - 505 с.
4. Оченашко О.В., Божков А.И., Петренко А.Ю. // Укр. біохім. журн. - 2002. - Т. 74. - № 3. - С. 25-30.
5. Оченашко О.В., Волкова Н.А., Петренко А.Ю. // Проблемы криобиологии. - 2002. - № 3. - С. 87-89.
6. Петренко А. Ю., Грищенко В. И., Оченашко О.В., и др. // Межд. мед. ж. - 2003. - № 3. - С. 121-126.
7. Петренко А.Ю., Ковалёв Г.А., Грищенко В.И. // Пробл. криобиол. - 2005. - Т. 15. - № 1. - С. 71-78.
8. Ben-Hur T., Idelson M., Khaner H., et. al. // Stem Cells. – 2004. - Vol.22. - № 7. - P. 1246-1255.
9. Bongso A., Richards M. // Best Pract Res Clin Obstet Gynaecol. – 2004. - Vol.18.- № 6. - P. 827-842.
10. Carnevale-Schianca F., Ricchiardi A., Capaldi A., et. al. // Transplant Proc. - 2005. - Vol. 37.- № 6. - P. 2664-2666.
11. Di Campli C, Piscaglia A.C, Rutella S., et. al. // Transplant Proc. – 2005. - Vol.37. - № 6. - P. 2707-2710.
12. Douglas A., Jero`nia L., Michael J, et. al. // The Journal of Neuroscience. – 2003. - Vol. 23. - № 12. - P.5131-5140.
13. Hoek J.B. // Hepatology. - 1999. - Vol. 29. - № 5. - P. 1602-1604.
14. Hovatta O., Meri S. // Ann Med. 2005. Vol.37. - № 7. - P. 466-468.
15. Hussain S.Z., Strom S.C., Kirby M.R., et. al. // Dig Dis Sci. - 2005. - Vol. 50. - № 10. - P. 1755-1763.
16. Jantunen E., Luosujarvi R. // Ann Med. – 2005. Vol.37. - № 7. - P.533-541.
17. Kindler V. // J. Leukoc Biol. - 2005. - Vol. 78. - № 4. - P. 836-844.
18. Liew C., Moore H., Ruban L., et. al. // Ann Med. – 2005. - Vol. 37. - №. - P. 7521-7532.
19. Shafritz D.A., Dabeva M. D. // Einstein Quart. J. Biol. Med. – 2002. - № 19. - P. 20-32.
20. Young H., Duplaa C, Katz R., et. al. // J Cell Mol Med. – 2005. - № 9. – P. 753-769.
The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.