SPIRONOLACTONE IN BIOFEEDBACK SESSIONS IN THE LOOP OF PACED BREATHING AND HEART RATE VARIABILITY IN HEALTHY VOLUNTEERS

  • E. Nazarenko
  • N. Nesterenko
  • O. Gh. Abdel Wahhab
  • S. Belal
  • O. Martynenko
  • M. Yabluchanskiy
Keywords: biofeedback, paced breathing, heart rate variability, regulatory systems of the organism, spironolactone

Abstract

In 7 conditionally healthy volunteers, aged from 19 to 21 years (average age is 19,53 ± 1,55 years), influence of spironolactone on alterations of regulatory systems state of the organism combined with biofeedback (BFB) sessions in the loop of paced breathing (PB) and heart rate variability (HRV) parameters was evaluated. All volunteers were conducted 2 series of everyday BFB sessions in analyzed loop for 5 days with a 3 months interval between them, 2nd series of sessions were conducted 6 hours after oral application of 25 mg spironolactone. The data was analyzed using non-parametric statistical methods. Optimization of regulatory systems state under influence of BFB sessions in the loop of PB and HRV parameters was found. Spironolactone in studied dose had no significant effect on optimization of regulatory systems state.

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Published
2016-04-24
How to Cite
Nazarenko, E., Nesterenko, N., Abdel Wahhab, O. G., Belal, S., Martynenko, O., & Yabluchanskiy, M. (2016). SPIRONOLACTONE IN BIOFEEDBACK SESSIONS IN THE LOOP OF PACED BREATHING AND HEART RATE VARIABILITY IN HEALTHY VOLUNTEERS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (30), 16-20. Retrieved from https://periodicals.karazin.ua/medicine/article/view/5644
Section
Clinical research