Effect of antihemolytic agents on the structural and functional state of erythrocyte membranes

Authors

  • N.V. Orlova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine Author

Keywords:

erythrocytes membrane, ESR, spine probes, dynamic structure, barrier function, amphiphiles

Abstract

By means of ESR using spine probes with various transmembrane localization a dynamic structure of erythrocyte membrane in the presence of amphiphilic compounds, possessing antihemolytic activity has been investigated. Non-specific modification of the structural and dynamic state of the surface and hydrophobic zone in erythrocyte membrane in the presence of amphiphilic compounds was demonstrated. The degree of the change in transmembrane microviscosity and physical and chemical membrane properties has been determined by polar groups of amphiphilic molecules.

 

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Author Biography

  • N.V. Orlova, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine

    23 Pereyaslavskaya str., Kharkov, 61015, Ukraine

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Published

2002-06-06

Issue

Vol. 1 No. 10 (2002): Біофізичний вісник

Section

Cell biophysics

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How to Cite

Effect of antihemolytic agents on the structural and functional state of erythrocyte membranes. (2002). Biophysical Bulletin, 1(10), 68-72. https://periodicals.karazin.ua/biophysvisnyk/article/view/18417