The physical model of non-specific endocytosis

Authors

  • E. V. Timofeyeva Institute for Problems of Cryobiology and Cryomedicine of NAS of Ukraine Author
  • E. A. Gordiyenko Institute for Problems of Cryobiology and Cryomedicine of NAS of Ukraine Author

Keywords:

endocytosis, physical model, free energy, deformation, membrane

Abstract

This work presents the physical model of non-specific endocytosis which is based on the hypothesis of periodical cell volume change, appearing from intracellular metabolic processes. Cell hydration leads to formation of domen, consisting of integral proteins, possessing their own negative spontaneous curvature. Further cell dehydration due to principle of minimum of free energy leads to formation of intracellular membrane bleb, separating from cell membrane

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Author Biographies

  • E. V. Timofeyeva, Institute for Problems of Cryobiology and Cryomedicine of NAS of Ukraine

    23 Pereyaslivska St., Kharkiv 61015, Ukraine

  • E. A. Gordiyenko, Institute for Problems of Cryobiology and Cryomedicine of NAS of Ukraine

    23 Pereyaslivska St., Kharkiv 61015, Ukraine

Published

2018-06-25

How to Cite

The physical model of non-specific endocytosis. (2018). Biophysical Bulletin, 1(12), 79-85. https://periodicals.karazin.ua/biophysvisnyk/article/view/12332

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