VASOMOTOR ENDOTHELIAL FUNCTION IN HYPERTENSIVE PATIENTS WITH RENAL ORIGIN

Authors

  • E. Kurshubadze
  • M. A. Vlasenko
  • O. O. Vlasenko

Keywords:

hypertension, chronic kidney disease, endothelial dysfunction

Abstract

The aim the study was to investigate endothelium dependent mechanisms that characterize the significance of endothelial dysfunction in hypertensive patients depending on its severity in patients with chronic kidney disease (CKD). A total of 73 patients with CKD: chronic glomerulonephritis 34, chronic pyelonephritis 22 and diabetic cardiomyopathy at the age of 22 (54,2 ± 6,2) years, men 52 and women 21. Endothelium depen­dent (EDVD) and endothelium independent (ENZVD) vasodilatation investigated by the method of D. Celer­majier et al.(1992). Compared with healthy individuals in patients with hypertension has been a significant reduction in both EDVD and ENZVD, and the emergence of a 2/3 of the low vasodilatation and constrictor re­sponses to compression and nitroglycerin. 

Downloads

Issue

No. 21 (2011)

Section

Clinical research

License

The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

How to Cite

VASOMOTOR ENDOTHELIAL FUNCTION IN HYPERTENSIVE PATIENTS WITH RENAL ORIGIN. (2015). The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", 21, 60-65. https://periodicals.karazin.ua/medicine/article/view/6897

Most read articles by the same author(s)