TY - JOUR AU - Osolodchenko, T.P. AU - Gorodnitskaya, N.I. AU - Shtiker, L.G. PY - 1970/01/01 Y2 - 2024/03/29 TI - ANTAGONIST ACTIVITY OF PSEUDOMONAS AERUGINOSA UNDER THE INFLUENCE OF ALLOSTERIC FERMENT ACTIVATORS JF - The Journal of V. N. Karazin Kharkiv National University, series "Medicine" JA - J. V. N. Karazin Khark. Nat. Univ., Ser. Med. VL - 0 IS - 16 SE - Fundamental research DO - UR - https://periodicals.karazin.ua/medicine/article/view/6977 SP - 17-20 AB - Clinic and vaccine strains of Pseudomonas aeruginosa and enhancers of izohinolins and imidazols class have been used for this study. The study focuses on the effect that these enhancers, both ceparatelly and in combination, have on antagonist activity of Pseudomonas aeruginosa. As a result of research it was рrovеd that the use of the allosteric ferment activators increases antagonist activity of Pseudomonas aeruginosa twice. Reciprocal antagonism was noted between clinical strains of Pseudomonas aeruginosa 15, 27, 87 and  vaccine strain of Pseudomonas aeruginosa 66-16, that is used to produce а vaccines. ER -