DEPENDENCE OF NEUROPSYCHOLOGICAL DEVELOPMENT OF EARLY AGE CHILDREN FROM THE FUNCTIONAL ACTIVITY OF SEROTONERGIC AND PITUITARY-THYROID SYSTEMS

  • H. O. Shlieienkova V.N. Karazin Kharkiv National University, Kharkiv, Ukraine
Keywords: neurologic status, psychological development, pituitary-thyroid system, serotonin, young children

Abstract

The high frequency of neurological disorders in children deprived of parental care was demonstrated (94.1 ± 2.2 %). The most commonly the syndrome of statokinetic, mental and pre-speaking retardation was diagnosed (49,2 ± 4,7 %, p < 0,001). High frequency disturbances of mental development and neurological status are accompanied by a reduction in the functional activity of the pituitary-thyroid system and the activation of serotonin. Between levels of thyrotropin and serotonin in the blood serum there is a moderate direct correlation (ρ = 0,56), which may indicate the adaptive increasing of the serotonin system activity, designed to compensate the lack of thyroid effects.

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Author Biography

H. O. Shlieienkova, V.N. Karazin Kharkiv National University, Kharkiv, Ukraine

Svobody sq., 6, Kharkiv, 61022, Ukraine

 

References

Badalyan L. O. Det·skaya nevrolohyya / L. O. Badalyan – M.: MEDpress-ynform; 2010. – 608 s.

Panʹkiv V. I. Praktychna tyreoyidolohiya / V.I. Panʹkiv. – Donetsʹk: Vydavetsʹ Zaslavsʹkyy O. YU., 2011. – 224 s.

Behrooz H. G. Subclinical hypothyroidism in pregnancy: intellectual development of offspring / H. G. Behrooz, M. Tohidi, Ya. Mehrabi [et. al.] // Thyroid. – 2011. – Vol. 21 (10). – P. 1143–1147.

Desai М. P. Thyroid Function in Children / М.P. Desai // Supplement To Jap. – 2011. – Vol. 59. – P. 35–59.

Bondarenko L. A. Yzmenenye struktury y funktsyy shchytovydnoy zhelezy v uslovyyakh éksperymentalʹnoho hypopynealyzma / L. A. Bondarenko, L. YU. Serhyenko, N. N. Sotnyk [y dr.] // Problemy éndokrynolohyy. – 2011. – № 2. – S. 32–35.

Mykhaylenko S. M. Vyznachennya vmistu serotoninu v plazmi krovi donoriv plazmy / S. M. Mykhaylenko, S. V. Vydyboretsʹ // Ukrayinsʹkyy zhurnal klinichnoyi ta laboratornoyi medytsyny. – 2011. – № 1 (6). – S. 139–141.

Chan Daisy K. L. Reference range of thyroid hormones in very low birth weight infants at the time of discharge / K. L. Chan Daisy, V. Togamolila, J. Ardhanari // Thyroid. – 2014. – Vol. 24, № 1. – P. 73–77.

Zelinsʹka N. B. Stan nadannya spetsializovanoyi dopomohy dityam z endokrynnoyu patolohiyeyu v Ukrayini u 2012 rotsi ta perspektyvy yiyi rozvytku / N. B. Zelinsʹka, A. V. Tereshchenko, N. P. Rudenko // Ukrayinsʹkyy zhurnal dytyachoyi endokrynolohiyi. – 2013. – № 3. – S. 31–39.

Kravchun N. A. Hypotyreoz: épydemyolohyya, dyahnostyka, opyt lechenyya / N. A. Kravchun, Y. V. Chernyavskaya // Problemy éndokrynnoy patolohyy. – 2011. – № 3. – S. 27–34.

Fadeev V. V. Po materyalam klynycheskykh rekomendatsyy Evropeyskoy tyreoydnoy assotsyatsyy po dyahnostyke y lechenyyu subklynycheskoho hypotyreoza u beremennykh zhenshchyn y detey / V. V. Fadeev // Klynycheskaya y éksperymentalʹnaya tyreoydolohyya. – 2014. – T. 10, № 3. – S. 20–26.

Practical Paediatric Endocrinology and a Limited Recourse Setting Editor Zacharin M.: Melburne, Australia, 2011. – 320 p.

How to Cite
Shlieienkova, H. O. (1). DEPENDENCE OF NEUROPSYCHOLOGICAL DEVELOPMENT OF EARLY AGE CHILDREN FROM THE FUNCTIONAL ACTIVITY OF SEROTONERGIC AND PITUITARY-THYROID SYSTEMS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine&quot;, (32), 48-55. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7827
Section
Clinical research