@article{Anikeeva_Gordiyenko_1, title={Cell adhesion: types, mechanisms, the role in functioning of living systems}, volume={1}, url={https://periodicals.karazin.ua/biophysvisnyk/article/view/2501}, abstractNote={<p>Current understanding of cell adhesion, its molecular mechanisms and significance are being considered.<br>Cell adhesion molecules (CAMs) (integrins, cadherins, selectins, mucin, immunoglobulin superfamily)<br>and its role in tissue formation, development of tumoral processes, immune and inflammatory reactions<br>were described. There are two types of adhesion: cell-matrix and cell-cell adhesions. Receptors of most<br>families CAMs involve in the adhesion at both types of interactions. According to most researchers,<br>adhesion occurs in two stages. The first (non-specific) stage is made by physico-chemical factors. The<br>specific interaction between adhesives and cell or matrix receptor at the molecular level occurs at the<br>second adhesion stage. Complexes formed by cell adhesion receptors are not static, but are dynamic units<br>capable of obtaining and incorporating extracellular environmental signals, and are indeed the foundation<br>of two-way signaling between the cell and its environment. Adhesive properties are critical for start and<br>maintaince of three-dimensional structure and normal tissue function.</p&gt;}, number={28}, journal={Biophysical Bulletin}, author={Anikeeva, M. O. and Gordiyenko, O. I.}, year={1}, month={1} }